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Varenicline, sold under the brand names Chantix and Champix among others, is a medication used for smoking cessation [5][7] and for the treatment of dry eye syndrome [6][8] It is a nicotinic acetylcholine receptor partial agonist [5][6] When activated, this receptor leads to the release of dopamine in the nucleus accumbens, the brain's reward center, thereby reducing cravings and withdrawal CHAMPIX smoking cessation studies have provided data in patients with a history of psychiatric disorders (see section 5 1) sychiatric disorders compared to those without a history of psychiatric disorders, regardless of treatment (see sectAs Canada's trusted pharmacy, Rexall provides detailed drug factsheets for Champix with common uses, dosage instructions, side effects & drug interactions What CHAMPIX is used for Champix is a medicine to help adults stop smoking It can help to reduce craving and withdrawal symptoms that may happen while you stop smoking People giving up smoking are often affected by nicotine withdrawal Symptoms of nicotine withdrawal can include craving for tobacco, irritability, frustration, feeling angry, sleep problems, depressed mood, feeling anxious Varenicline is a pill that does not contain nicotine You need a prescription for it It works differently than other quit-smoking medicines and may be an especially good option for people who have tried using other medicines to quit before but haven’t been able to quit successfully Varenicline comes in two strengths: 0 5 mg (a white pill) and 1 mg (a blue pill) Your doctor or pharmacist Champix ® increased the likelihood of abstinence from smoking for one year compared with placebo in patients suffering from acute (including unstable angina and myocardial infarction) and chronic cardiovascular diseases Jan 7, 2026 · Learn about the side effects of Champix (varenicline), from common to rare, for consumers and healthcare professionals Sep 11, 2025 · Champix is a medicine that contains the active substance varenicline It is available as tablets (0 5 and 1 mg) Medical information for Champix including therapeutic indications, usage and dosage instructions, plus benefits and possible risk factors About varenicline Varenicline (previously called Champix) is a medicine that can help you stop smoking The addictive part of cigarette tobacco is called nicotine Varenicline can reduce the cravings for nicotine and helps with the withdrawal you get when you stop smoking