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Along with its needed effects, fluorouracil topical (the active ingredient contained in Efudex) may cause some unwanted effects Although not all of these side effects may occur, if they do occur they may need medical attention Check with your doctor immediatelyif any of the following side effects occur while taking fluorouracil topicalec 13, 2025 · Get clear safety guidance for Efudex, including warnings, precautions, when to seek medical assistance, and how to use it correctly youtube comNov 13, 2025 · Efudex not working? Learn why there may be no reaction, what to do during treatment, and alternative options for non-responsive actinic keratosis or skin cancer See full list on drugs comyoutube comJul 13, 2022 · Hi, I've been using Efudex 5% twice a day for three weeks on one cheek due to AK and an IEC I've had quite a mild reaction - nothing until day 7 and then some slowly reddening AKs some of which now look a bit dried out Another factor to consider is that Efudex doesn’t necessarily show signs of working DURING the treatment The scabbing may not begin developing until a week or so after the last application youtube comI started the Tolak cream last Tuesday evening (4 16) and today (4 25) my skin looks no different at all, it's not even dry I know I have sun damage on my face, not 100% sure there are any AK's, but I'm not even a little bit pink anywhere Jul 17, 2025 · For two weeks, I snapped on a surgical glove and applied a thin layer of Efudex and a vitamin D derivative called Calcipotriene all over my face and chest, once in the morning and once before bed